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For example, severe diarrhea can lead to anal fissures, while constipation may cause hemorrhoidal bleeding from straining

Dapagliflozin 10 mg was superior to placebo in reducing the incidence of the primary composite endpoint of hospitalization for heart failure or CV death [HR 0.83 (95% CI 0.73, 0.95)]

These medications can also be beneficial for people with obesity or those who need help managing their weight due to other health conditions

Measurable weight loss usually becomes apparent by weeks 3-4

Dulaglutide: Sold under the brand name Trulicity, dulaglutide is a once-weekly injection that is FDA-approved for managing diabetes (6)

The gut-brain axis means that significant microbiome changes can affect mood and anxiety levels