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Approaches to improvements in efficacy primarily target additional gut hormones via dual- and tri-agonists, and if Mounjaro provides any indication, dual- and tri-agonists may not be likely to enhance tolerability

Slow gastric emptying: They signal certain nerves to slow down the movement of food from the stomach into the intestine

Although underlying mechanisms are still not completely explained, the interaction with RAAS seems to play a relevant role

Covering drugs that can cost hundreds of dollars per patient every month only pays off if patients stay on therapy

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Tirzepatide is a large protein molecule