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Practical strategies for emotional well-being A few proactive habits can help protect your mental health during GLP1 treatment: Prioritize protein intake : Aim for adequate protein at every meal to support serotonin production and prevent the muscle loss that can contribute to fatigue and low energy

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This might include: Eating smaller meals to help your body adjust to slower digestion Drinking more water to help prevent dehydration Getting more fiber in your diet to help with constipation Taking an anti-nausea medication to help with vomiting or queasiness Avoiding certain foods , such as rich, greasy, or sugary foods, that can worsen digestive side effects Rare but serious side effects and warnings These drugs may also come with some rare but serious side effects, including: Diabetic retinopathy complications in people with type 2 diabetes

They can be effective, but most people stop taking them within months, and weight often returns when they do

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In particular, GLP-1 analogues have shown direct effects on the plasticity of the pancreatic islet in both normal glucose tolerance and throughout the whole spectrum of alterations leading to overt diabetes [7]