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doi: 10.1016/S0140-6736(21)01324-6

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Potential adverse effects of metformin Tips on prescribing metformin Metformin AND topiramate for metabolic adverse effects

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The adipocyte is an important site of triglyceride metabolism [29] and is unique in its expression of the GIPR and not the GLP-1R

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A ) Mean images of brain activation at baseline and week 6 and B ) least squares mean (standard error) change in BOLD fMRI parameters for highly palatable foods vs non-food objects at week 6

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Clinical Trial Results Clinical trials have highlighted its efficacy, with participants experiencing significant weight reductions: Mounjaro Study Results: The SURMOUNT-1 trial (NEJM 2022) showed individuals with obesity losing up to 2022.5% of their body weight, surpassing many other weight-loss drugs in the market

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