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Dr Sindy Newman, who is a leading weight loss medication expert from Diet UK, told The Irish Mirror/Star: "In Ireland and across the EU, the only oral GLP-1 medicine currently authorised is Rybelsus (semaglutide tablets), which is licensed for type 2 diabetes and sometimes prescribed off-label for weight loss

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We eat to a volume target, which means, by definition, hey, if you can lower the energy density of what's going in your mouth, what's on your plate, you can eat the same physical amount of food and ingest fewer calories without feeling deprived

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Table 1 illustrates that the most significant obstacles to progress across these systems have not been a lack of physiological relevance, but unresolved pharmacologic, technological, or conceptual challenges