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Semaglutide is most effective when paired with lifestyle and dietary changes

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Excretion of about 30% of ingested triglycerides, which is close to the maximum plateau value, occurs at a dose of 360 mg/day (120 mg three times daily with meals) [14]

This regulatory context is important: both medicines sit outside standard NHS prescribing pathways for most patients, and robust safety data in real-world UK populations is limited

According to American Diabetes Association guidelines, all patients with type 2 diabetes should receive comprehensive dilated eye examinations by an ophthalmologist or optometrist at diagnosis