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95% CI 0.8, 2.4)

GLP-1 is secreted physiologically by enteroendocrine L-cells of the small and large intestine, and GIP is secreted by duodenojejunal K-cells in response to food intake [23]

doi: 10.2174/1570159X18666200528142429 31 AlberdiEWyssenbachAAlberdiMSnchez-GmezMVCavaliereFRodrguezJJet al
shows that in participants with type 2 diabetes mellitus with high cardiovascular risk, those receiving the GIP/GLP-1R dual agonist, tirzepatide, had a significantly lower rate of composite renal endpoints, a significantly slower rate of decline in eGFR and a significantly lower urinary albumin creatinine value compared to those receiving glargine insulin [36]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 9.Apovian C.M., Aronne L.J., Bessesen D.H., et al
