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In another study on semaglutide sponsored by Novo Nordisk, researchers found a 20 percent reduction in major adverse cardiovascular events among people with overweight or obesity and preexisting cardiovascular disease

The larger REMAIN-1 study includes more than 300 participants and is fully enrolled and randomized

[DOI] [PMC free article] [PubMed] [Google Scholar] 290

High baseline BMI individuals generally lost the most weight

Novo launched the oral drug in the United States earlier this year after winning FDA approval, giving it an early start

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