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After a 4-week run-in period in which participants were treated with diet and exercise alone, those who fulfilled the randomisation criteria were randomised (1:1:1:1) using a web-based randomisation system to receive once-daily oral semaglutide 3 mg, 7 mg or 14 mg or placebo for 26 weeks (using a 4-week dose-escalation regimen for the higher doses)

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Weve discussed the hockey-stick rise in the adoption and persistent use of GLP-1 drugs for managing diabetes and obesity here in Health Populi

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A little over a week after announcing that the Evoke and Evoke+ studies failed to show that oral semaglutide could slow cognition decline in patients with Alzheimers disease, investors and researchers got the first look at the actual data from the studies, which were presented at the Clinical Trials on Alzheimers Disease 2025 meeting.