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Factors such as side effects, high out-of-pocket costs, injection fatigue and stigma around obesity treatment drive troves of patients some studies estimate roughly half or more to stop GLP-1s within a year and risk regaining the weight they lost

Blocks the kidney protein that pulls glucose back into your blood, helping excrete sugar

95% CI 0.89, 0.96) and all-cause mortality rate (HR 0.70

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GLP-1 therapies reduce inflammation across organs through rapid, weight-independent immune and metabolic effects.

Cheaper copies mean many more people will likely start taking these drugs, and not always under close specialist supervision, even though the rules say only certain doctors are allowed to prescribe them