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Description
22,23 Obese HFpEF patients have greater LV hypertrophy and pulmonary capillary wedge pressure, increased LV filling pressures and severe right ventricular dysfunction compared with non-obese HFpEF patients

However, unlike GLP-1R agonists, DPP-4 inhibitors do not cause significant reductions in body weight (Meneghini et al., 2011

The primary fallacy lies in viewing the GLP-1 market as a zero-sum game

Clin Endocrinol (Oxf) 2014

Our understanding of the disease mechanisms and molecular targets of drugs has been facilitated by new biotechnology advances, such as RNA sequencing

Acute activation of GLP-1-expressing neurons promotes glucose homeostasis and insulin sensitivity
