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Image: Freepik No clinical trials have directly tested berberine and semaglutide together, but the combination is likely safe under medical supervision based on their distinct mechanisms

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Across the SLD spectrum, GLP-1 RAs demonstrated modest but directionally consistent improvements in liver enzyme profiles (alanine aminotransferase [ALT] and aspartate aminotransferase [AST]), with 4 of the 7 ALT outcome estimates showing significant reductions, and 4 of the 9 AST outcome estimates showing significant reductions

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OP 04 Behind the screens: adventures in type 1 diabetes clinical trials OP 05 Did we underestimate the role of gut microbiota in the pathogenesis of diabetes

KD outperforms other diets in many respects, including appetite and hunger suppression, greater initial weight loss, superior anti-inflammatory effects, better regulation of glycaemia and insulinaemia, and psychological benefits [21]