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Tresiba typically causes weight gain of 1 to 4 kg, which is the opposite of GLP-1 medications that produce significant weight loss

Boosted mental well-being: Achieving weight loss goals can positively impact mood and self-esteem

The dipeptidylpeptidase-IV inhibitors sitagliptin, vildagliptin and saxagliptin do not impair innate and adaptive immune responses

5.8%) in the year following their PMOS diagnosis compared to non-initiators, while hormonal birth control use was similar in both groups (32.6% vs

Side Effect Profiles The most noticeable practical difference is that dual agonists like tirzepatide tend to cause slightly more gastrointestinal side effects than pure GLP-1 agonists

If patients have a severe obesity-related complication including but not limited to hypertension, type 2 diabetes, CVD, dyslipidemia and a BMI of 27 mg/kg 2 or greater, then concurrent initiation of weight-loss medication with lifestyle interventions can be considered, according to the guideline