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Bisphosphonates work by impairing osteoclast function, slowing the rate of bone resorption, and thereby allowing the osteoblast-driven bone formation process to gain relative ground

Unfortunately, rapid weight loss can stress the body and disrupt the normal hair cycle, causing shedding. Nutritional deficiencies and hormonal shifts common during medical weight loss may worsen this effect

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Long-term adherence: The effectiveness of medications relies on consistent use

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However, a pooled analysis of liraglutide trials demonstrated that blood pressure lowering occurs within two weeks of treatment initiation, suggesting other effects on vasculature beyond weight loss [36]