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Use of glucagon-like peptide 1 agonists for weight loss compared with bupropion-naltrexone was associated with an increased risk for pancreatitis, gastroparesis and bowel obstruction but not biliary disease, researchers reported in JAMA

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By using LLM's to structure thousands of realworld patient stories, the team surfaced: The usual suspects (GI side effects) at scale Underdiscussedmenstrual changes and reproductive symptoms Temperaturerelated complaintslike chills and hot flushes High rates offatiguethat dont feature as prominently in trial reports None of this proves causation