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For nasopharyngitis, heterogeneity was determined by I statistic, which suggested heterogeneity (I=0%, p=0.71), providing rationale for employing fixed-effects model

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One patient reported that two months after she began taking the drug, she realized the skin on her back, which she had compulsively picked for years, had healed

The placebo-subtracted fibrosis improvement was highly significant and in the range of prior agents considered in the MASLD field as antifibrotics, such as obeticholic acid (Intercept Pharmaceuticals), which was not approved by FDA for MASH on safety concerns) or resmetirom (Rezdiffra, Madrigal Pharmaceuticals), which is the first FDA-approved agent for the treatment of MASH

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