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Liraglutide (25 nmol/kg/day) treatment reduced the mRNA expression of proinflammatory cytokine genes, which was induced by X-ray irradiation [24]

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Additionally, the bidirectional relationship between sleep disturbances and addiction has been increasingly recognized: substance use disrupts sleep architecture, while sleep disorders themselves may predispose to relapse and worsen addiction outcomes [38]

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Testing these hypotheses merits future effort, as does reconsideration of the previous literature that has shown positive attributes of GIPR agonism for beta cell function 10,42,43

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