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ectopic fat deposition in the liver and epicardium triggers inflammation, disrupts myocardial energy metabolism, and promotes fibrosis, contributing to cardiac dysfunction and diastolic impairment

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Microneedle patch with pure drug tips for delivery of liraglutide: pharmacokinetics in rats and minipigs

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Semaglutide has been used for diabetes management for years, with no emerging safety signals in long-term follow-up

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The dataset presented here also indicate that the PI3K/mTOR pathway plays a crucial role in mediating GLP-1R signalling effects on energy metabolism

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Fuselier et al., 2022)

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