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ectopic fat deposition in the liver and epicardium triggers inflammation, disrupts myocardial energy metabolism, and promotes fibrosis, contributing to cardiac dysfunction and diastolic impairment

Microneedle patch with pure drug tips for delivery of liraglutide: pharmacokinetics in rats and minipigs

Semaglutide has been used for diabetes management for years, with no emerging safety signals in long-term follow-up
The dataset presented here also indicate that the PI3K/mTOR pathway plays a crucial role in mediating GLP-1R signalling effects on energy metabolism

Fuselier et al., 2022)
