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The hormone, called glucagon-like peptide-1, helps regulate blood sugar.by promoting the secretion of insulin

Unfortunately, these peptides require parenteral administration, due to instability in the proteolytic milieu of the digestive tract, making it impossible to deliver adequate drug reproducibly via oral route

Schlessinger points out that many patients in these studies already had advanced disease before starting treatment, which makes it difficult to pin new changes directly on the medication

Outcomes improved

By starting with or maintaining lower doses, providers hope to balance effectiveness with tolerability

It also promotes satiety, or a feeling of fullness