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GLP-1 Reduces appetite, slows gastric emptying GIP Enhances insulin, improves fat metabolism Glucagon Increases energy expenditure, burns fat Based on Phase 2 clinical trial data (published in NEJM, 2023), retatrutide's side effects are primarily gastrointestinal, similar to other GLP-1 agonists but with some differences due to the glucagon component

Step 5: Expect to receive your medication within 7 to 10 business days from the date it is shipped

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However, you may experience nausea, vomiting, diarrhea, or constipation

## The Oral GLP-1 Landscape in 2026 The treatment of obesity is entering a new phase defined by oral medications

Although this medication helps in lowering blood sugar, it may sometimes lower it too much