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This approach is for people with a BMI above 50, severe diabetes or who'd like to lose 200 pounds or more

In depression, placebo arms routinely move 10 to 12 points on MADRS, and that wall has buried more novel mechanisms than bad biology ever has

Timing around GI episodes After any episode of vomiting or diarrhea, electrolyte replacement should happen within 30 minutes

Theres a loophole for companies to continue selling compounded versions

If you stop taking them without maintaining healthy habits, you may regain weight

Over the following weeks, as your dosage is gradually increased and your body responds more fully, weight loss tends to become more noticeable