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Post-transplantation diabetes mellitus

Vagal afferent neurons (VANs) expressing GLP-1Rs innervate intestinal mucosa and hepatic portal vasculature, suggesting these pathways may transduce peripheral GLP-1 RA effects to central satiety and glucoregulatory centers 57,58,59

Most importantly, this study highlights the need for continued dermatologic awareness as systemic medications evolve and are used at scale

Beyond weight loss: the emerging role of incretin-based treatments in cardiometabolic HFpEF

For the GLP-1 drug pipeline, 2026 is not a consolidation year

The Phase 2 program generated the key proof-of-concept data that propelled orforglipron into one of the largest Phase 3 development programs in metabolic disease