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No Clinical Data on Microdosing Specifically Every clinical study on retatrutide so far has used standard therapeutic doses

The 52-week duration of treatment was relatively short, and whether the observed effects might have persisted (or become more amplified) with longer evaluation is not known

Some studies suggest tirzepatide may cause slightly more digestive side effects, but individual responses vary

The possible role of phentermine has not been established, therefore the possibility of an association between heart valve disease and the use of phentermine alone cannot be ruled out

Anyone facing surgery or endoscopy should tell their doctor, as the dose may need to be paused

While semaglutide targets only the GLP-1 receptor and Tirzepatide targets both GLP-1 and GIP receptors, Retatrutide additionally targets the glucagon receptor