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In the subgroup analyses, human GLP-1 RAs, but not nonhuman GLP-1 RAs, reduced the risk of MACE in patients with HF (p interaction = 0.11)

Large real-world study shows tirzepatide and semaglutide offer similar protection from heart attack, stroke, and death.

muscle), in addition to seeing improvements in glycaemic control10

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The phase 3 TRANSCEND-T2D-1 trial evaluated the triple GIP, GLP-1, and glucagon receptor agonist in adults with type 2 diabetes inadequately controlled with diet and exercise alone.

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