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Clinically studied for greater weight loss than GLP-1 alone

Switching to the oral small molecule glucagon-like peptide-1 (GLP-1) orforglipron after taking injectable GLP-1s helped patients maintain mostbut not allof their weight loss, according to a clinical trial led by Weill Cornell Medicine and NewYork-Presbyterian investigators.

Costs of prescription drug coverage in the FEHB program rose from just under $10 billion in 2019 to about $14 billion in 2024, with a main driver being a

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