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Additionally, the agonist-independent (basal) activity of GIPR is much higher than that of GLP-1R, which essentially displays no constitutive activity [37]

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This is a normal biological process known as metabolic adaptation

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Several elements of Kind Patches' marketing the customer survey numbers, the implication of GLP-1-like effects, claims about "supporting GLP-1 production" sit close to or in this territory