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Chronic vagus nerve stimulation decreased weight gain, food consumption and sweet craving in adult obese minipigs

Patients with a personal history of MTC or a family history of MTC or MEN 2 should not receive tirzepatide

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Diabetes treatment medications like insulin: Insulin and some oral diabetes medications, such as sulfonylureas, can increase your risk for hypoglycemia when used with tirzepatide

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As weight loss increases the lithogenicity of bile, it remains unclear whether the increased risk of biliary disease seen with GLP-1 receptor agonists is due to the medication itself or to weight loss