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Bradley et al., 2012) or a decrease in energy expenditure (van Can et al., 2014)

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Medical records should address and exclude conditions such as giant cell arteritis, severe hypertension episodes, recent eye surgery, or other medications known to affect optic nerve function

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The GLP-1R is part of the glucagon family of receptors, including the glucose-dependent insulinotropic polypeptide receptor (GIPR) (5), the glucagon receptor (GCGR) (12), and the glucagon-like peptide-2 receptor (GLP-2R) (13), which are class B1/secretin-like G protein-coupled receptors (GPCRs) with a typical structure of seven transmembrane domains (7-TMD), a C-terminal tail, and a large N-terminal extracellular domain (ECD) important for peptide agonist binding (14)

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doi: 10.1007/s12640-014-9492-x

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Kitzman DW, Nicklas BJ (2018) Pivotal Role of Excess Intra-Abdominal Adipose in the Pathogenesis of Metabolic/Obese HFpEF

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