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Role of funding source The funder of the study provided study drugs and was involved in study design, data collection, data analyses, data interpretation and writing of the report

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Other factors such as number of force majeures declared, existing client base and warnings issues by regulatory agencies are some of the aspects on which CDMOs might be regularly assessed

ACKNOWLEDGMENTS The writing group acknowledges the contribution of Dr Scott Isaacs, who reviewed and provided advice on the Endocrinologic considerations and Adverse events and safety monitoring sections of this manuscript

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