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If youre experiencing joint pain while taking tirzepatide or other GLP-1 medications, these evidence-based strategies may help minimize your discomfort: Exercise plays a critical role in maintaining joint health during rapid weight loss: One study of patients on GLP-1 medications found those who maintained consistent strength training reported 40% less joint discomfort than sedentary participants

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When to Seek Immediate Medical Help Seek immediate medical care for gastroparesis if you experience severe dehydration (dizziness, little/no urination, extreme thirst), uncontrollable vomiting for over an hour, or severe abdominal pain

It is a combination of a GLP-1 agonist and an amylin agonist, explains Richard Siegel, MD, co-director of the Diabetes and Lipid Center at Tufts Medical Center and endocrinologist at Tufts Medicine Weight & Wellness Center Stoneham