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In one study, more than half the participants (54%) had no previous use of oral glucose-lowering medication [22], while in another study, all participants were on a stable dose of insulin glargine with (83%) or without (17%) metformin [19]

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In a post hoc analysis, presented at ESC 2025 and including ~750 participants who completed 72 weeks of treatment, 10year cardiovascular disease (CVD) risk was estimated using validated BMIbased Framingham equations

Even with a 0.3 ml syringe, measuring 2.5 units accurately is difficult

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Understanding body composition changes during treatment is essential for setting realistic expectations and implementing strategies to preserve lean tissue