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This also had an impact on sensitivity analysis 4, which adjusted for baseline HbA1c and body weight in patients on metformin in SURPASS2 and patients on metformin with or without a sulphonylurea in SUSTAIN FORTE

Furthermore, the trim and fill model did not identify any missing studies, corroborating the robustness of the findings

TK wrote the first manuscript draft

Phase 3 clinical trials are underway, with promising results beyond even weight loss

Meta-analysis in clinical trials

Efficacy and safety of LY3298176, a novel dual GIP and GLP-1 receptor agonist, in patients with type 2 diabetes: a randomised, placebo-controlled and active comparator-controlled phase 2 trial