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This kind of rigorous, data driven analysis is exactly what our field needs to move the conversation from "are NAMs ready?" to "are we benchmarking them fairly?" The bar for NAMs should be high and we are actively advocating for validation guidelines for specific NAMs models
The term solubility in the BCS report refers to the therapeutic dose of a drug that is soluble in an aqueous media which has pre-specified characteristics (volume, pH and temperature)
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