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Description
Summary: NICE guidance advises against combining Trulicity (a GLP-1 receptor agonist) and Januvia (a DPP-4 inhibitor), recommending that DPP-4 inhibitors be discontinued when starting GLP-1 receptor agonists
A phase II trial in GHD adults (n=32) reported IGF-1 normalization in 5075% of participants at 30120 g/kg monthly, which was observed to be comparable to daily GH therapy [pubmed.ncbi.nlm.nih.gov]
It is also used to minimize the risk of cardiovascular events, including Stroke and heart attack, in certain adults with Obesity
Significant acute reductions in appetite and food intake were initially observed after intravenous (IV) administration of GLP-1 both in healthy individuals and in patients with T2D
Cuadrado A, Manda G, Hassan A, Alcaraz MJ, Barbas C, Daiber A, et al
(And so does my wife, since I dont snore anymore.) But its also because I feel optimistic
