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Tell all your healthcare providers that you are taking Wegovy before you are scheduled to have surgery or other procedures The most common side effects of Wegovy may include: nausea, diarrhea, vomiting, constipation, stomach (abdomen) pain, headache, tiredness (fatigue), upset stomach, dizziness, feeling bloated, belching, low blood sugar in people with type 2 diabetes, gas, stomach flu, heartburn, and runny nose or sore throat.

NHS England intends to provide the weight-loss drug semaglutide to over 1.2 million people with cardiovascular disease who are overweight, following guidance that demonstrates its effectiveness in reducing the risk of heart attacks and strokes People with heart and circulatory disease who are overweight will be able to receive Semaglutide from summer 2026, following approval by the National Institute for Health and Care Excellence (NICE) after securing a cost-effective deal for the NHS

GLP-1 agonists have emerged as promising therapeutic agents for diabetic cardiomyopathy through multiple protective mechanisms

Intestinal microbial sulfatase can promote melatonin secretion ( Mtnr1ba and Mtnr1bb ) (Lutfi et al., 2021)

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