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Description
Muscle mass naturally declines with age unless it is actively maintained
Since its clinical application in 1957, metformins cornerstone status has remained consistent and it is still the first-line preferred treatment for type 2 diabetes mellitus (T2DM) side by side with lifestyle (Montvida et al., 2018

Diabetes Care 2021;44:983-992 Gaudieri PA, Chen R, Greer TF, Holmes CS

Close monitoring is essential, with clear parameters established for escalating to dose reduction or discontinuation if symptoms worsen

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How retatrutide compares to semaglutide and tirzepatide for muscle preservation Comparison drives clarity
