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However, some types of eating disorders could worsen with GLP1-RA and require monitoring and treatment by registered dietitian and/or behavioral health providers who specialize in eating disorders, with appropriate referrals to higher levels of care for disordered eating.

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Since 2021, GLP-1s have eroded metformin as the preferred first-line therapy for many patients, despite metformins lower cost and oral administration

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Between-study heterogeneity was very high (I = 99.21%) although sensitivity analysis revealed that the findings were robust