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It can cause apathy, anxiety

Like GLP-1, OXM is rapidly degraded in the circulation by DPP-IV

If nausea persists beyond 10 to 14 days at a new dose level, extend your stay at that dose for an additional 2 to 4 weeks before attempting escalation again

However, not all weight loss plateaus on semaglutide are a result of the drug losing potency, even if you arent at the maximum dose

Understanding where each model sits helps operators evaluate which approach fits their brand, resources, and risk tolerance