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Patients on stable levothyroxine doses who add semaglutide typically maintain their thyroid medication without adjustment, though ongoing monitoring ensures continued balance

Instead of stopping medication suddenly, some people may transition gradually to lower doses

Storage and Handling Researchers are responsible for determining appropriate storage conditions, handling procedures, and disposal methods relevant to their specific research applications, in accordance with standard laboratory practices and applicable regulations

Lentiviruses were generated by co-transfection of each shRNA construct with envelope plus packaging vectors (pMD2.G, Addgene #12260 and psPAX2, Addgene #12259) and viral supernatants purified by ultracentrifugation onto 20% sucrose gradients

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