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Description
Safety and efficacy in pediatric populations have not been established
In the STEP 2 trial, adults with obesity or overweight plus type 2 diabetes lost a mean 9.6% of their body weight at 68 weeks with semaglutide 2.4 mg vs
Opting for these aligns better with insurance requirements, as insurers tend to cover medications according to their approved indications
Weight loss accelerates
Conclusion: Data from all randomised placebo-controlled trials with semaglutide and liraglutide do not suggest an increased incidence rate of NAION in participants randomised to GLP-1RA treatment versus those receiving placebo
Readers interested in a more detailed discussion are referred to the review by Angera et al
