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Just how much of a challenge this posed can be gauged from the fact that Mutt's group needed 10km of porcine small intestine to obtain about 1mg of pure secretin (Rehfeld 2012)

Mechanisms underlying metformin-induced secretion of glucagon-like peptide-1 from the intestinal L cell

References American Diabetes Association Professional Practice Committee

Retrieved 20 September 2019

If its dark or has a strong odor, you likely need more fluidsespecially if you're also experiencing fatigue or dizziness
This positions the drug as a potential preemptive treatment
