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Key Background Adverse side effects may also be causing a decline in GLP-1 use among people with type 2 diabetes
Bariatric surgery for qualified individuals is the next option if lifestyle changes and pharmacotherapy are unable to meet individualized weight loss goals [132]

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If you feel you may benefit from a medication such as CONTRAVE, please discuss a treatment plan with your doctor

Based on TRIUMPH-4's results and the completed TRIUMPH-1 general obesity trial (28.3% weight loss in 2,339 patients, May 2026), Eli Lilly is expected to submit a New Drug Application in Q4 2026
