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GLP use among people with preexisting SUDs was linked to reduced hospitalization, overdose, and mortality

They also act on appetite centres in the brain, reducing hunger and food intake

10.1111/dom.14089

These side effects can be intense enough for an estimated 10% to 20% of patients to stop using GLP-1s, and they tend to be dose dependent meaning that the higher the dose, the more intense or frequent the side effects can be

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