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33 Similar findings were observed in a meta-analysis of 40 trials which concluded that GLP-1RAs were highly effective at lowering circulating glucose levels without causing hypoglycemia

[DOI] [PMC free article] [PubMed] [Google Scholar] 28.Drucker DJ, Brubaker PL

Three studies investigated the effect of liraglutide, an approved GLP-1 agonist for the treatment of obesity

While GLP-1RA has proven clinical efficacy, the need for more comprehensive studies, to ensure their long-term safety, is essential to optimize their therapeutic role and improve patient outcomes on a global scale

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In accordance with US Food and Drug Administration guidelines, a meta-analysis of cardiovascular events in several phase 2 and phase 3 studies has been reported
