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One of the concerns about GLP-1 agonists is a higher percentage loss of lean body weight or muscle mass than weight management achieved through diet and lifestyle changes

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Depression and metabolic syndrome: a vicious cycle Depression is closely linked to metabolic syndrome, a cluster of conditions including abdominal obesity, dyslipidemia, hypertension, and T2DM
The differences in weight loss between SELECT and STEP I highlight the crucial role of comprehensive care beyond medication

Funding This paper was supported by the National Institute for Health and Care Research (NIHR) Leicester Biomedical Research Centre
