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This data suggests that tirzepatide itself does not substantially elevate pancreatitis risk above baseline population rates when used as directed

In such cases, exploring a tirzepatide alternative or reviewing alternatives to tirzepatide that pair more comfortably with berberine may be worth considering

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No, GLP-1s are considered adjunctsthey do not replace disease-modifying drugs but can be a helpful addition in select patients to improve metabolic and inflammatory status.
