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GIP Receptor Limb GIPR engagement is the distinguishing feature separating dual agonists such as tirzepatide from single GLP-1R agonists

3,249 patients were excluded due to missing demographics, age 40 years, missing demographics, prior use of any study drug, diagnosis of type 1 DM, retinal disorders classified based on the ICD categories (DR, retinal vascular occlusion, separation of retinal layers [including all types of retinal detachment and central serous retinopathy], degeneration of retina, chorioretinal inflammations, and other retinal disorders [including retinal hemorrhage, vitreous hemorrhage, retinal edema, etc.]), history of receiving vitreoretinal interventions (intravitreal injection, laser coagulation, and vitrectomy), no baseline glycosylated hemoglobin (HbA1c), or no follow-up data in the subsequent 6 months after being prescribed the medication, were excluded from this study

doi: 10.1002/jnr.490160110

The maintenance of long-term weight loss after semaglutide withdrawal in obese women with PCOS treated with metformin: a 2-year observational study

A standard program steps the dose up over time toward a high target

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