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The study sample included 817,309 patients with alcohol use disorder and 503,747 patients with opioid use disorder

The key consideration is timing: the sooner you recognize and address the missed dose, the less disruption to your treatment regimen

Its ability to reduce weight significantly and improve metabolic health makes it a breakthrough therapy

At 10mg, clinical trials showed 21.4% average body weight loss, approximately 49 pounds from a 230-pound starting weight

Metabolic improvements include enhanced insulin sensitivity, reduced hepatic steatosis, favorable lipid changes with LDL and triglyceride reductions, and improvements in systemic inflammation markers

While more research is needed, the data hint at a potential protective effect on joint tissues themselves