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Access to treatment then comes down to families who can afford to pay for it out-of-pocket, which creates an equity issue and forces children who could benefit the most from intervention to stop, Shah said

This warning was not included in the initial drug-warning labels of many semaglutide drugs

Nausea is the most frequently reported complaint, occurring in 28% of participants on the 12mg dose

For the first time in the programs history, Medicare will provide coverage for weight loss drugs through a temporary initiative aimed at making the medications more affordable for eligible seniors

As previously noted, even the lowest effective 4mg aw dose provided compelling health benefits It will be compelling to see how triple-agonist therapy is tolerated in the long term especially given that single and dual incretin-based therapies show substantial discontinuation rates in real-world settings, in some cohorts approaching 70%

Retatrutide's approximately 6-day half-life is what makes once-weekly dosing appropriate