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Even well-resourced insurers struggle to manually review every GLP-1 request

However, both studies indirectly assessed gastric emptying through paracetamol absorption testing, a method limited by its inability to quantify the actual volume or consistency of gastric contents [36]

40 Therefore, current data suggest that GLP-1 RAs do not improve exercise capacity in HFrEF

Cardiovascular-risk coverage under private plans in So Paulo already rose in 2025, and Mexicos ISSSTE is examining similar add-on benefits for 2027

[DOI] [PubMed] [Google Scholar] 75.Bible KC, Kebebew E, Brierley J, Brito JP, Cabanillas ME, Clark TJ Jr, et al

These benefits were further supported by the results of the SUMMIT trial, which investigated tirzepatide, a dual GLP-1/glucose-dependent insulinotropic polypeptide receptor agonist, in patients with HFpEF with or without T2D